The Job Monos have the same sound signature of the 225 (speed/cleanliness/transparency) but adds grunt when called upon with more challenging speakers. For my bookshelves, I really could not realize any difference.
For the floorstanders, I got a pal to lend me another sweetcord, as I only own one, and ther I could tell a bit of a difference. Mind you, my speakers have small woofers. I suspect with real full range monolithic type transducers, the extra grunt will be seen/felt immediately.
The Job amps also respond to type of preamp used. I had use a carbon pot passive and when I switched to a powered LDR passive pre and blammo...MUCH better. The 250s sang even more than the 225. The whole thing gave me mad respect for the 225 though, as unless you need that extra grunt, the 225 will more than suffice to kep you happy.