I have 3 switches in series in my chain, but for logistical convenience than any intentional audiophile reason.
Fiber internet enters the house thru the ONT and passes in and out of a wifi-enabled router (which technically counts as a switch). From there it goes to the main switch located in the big distribution rack in the basement. Upstairs in the 2-channel setup I have a second much smaller switch connected to the primary that feeds the dedicated stereo gear. Why? I simply don't have enough ethernet cable running through the walls for each device to have its own home run to the main switch. This approach lets me send one cable to the AV cabinet and re-distribute from there. Bandwidth requirements are ultimately small, and almost never require more than one device to be actively pulling data. If I'm streaming audio via the Aurender, the DAC and nearby video devices aren't, and vice versa. Given that Aurender supposedly caches an entire streaming track before starting playback, I'm not too concerned about dropped packets or jitter introduced during transmission (and my network pings at under 1ms of jitter, so it's pretty clean to start with).
I've been happy with the end result of the mess described above. Perhaps there's more optimization possible, but I feel like it already checks most of the boxes the dedicated audiophile gear achieves - particularly being on fiber internet to deal with any galvanic issues at the source. No wifi to the audio gear - yeah, it's in the air, but the audio gear's radios are all off. I admit I've never tried the dedicated audio switches described here, but potentially the small one located by the 2-channel rig could be a candidate for that kind of experimentation. I guess I won't know until I try it...