No, get the room fixed as far as possible with sensible furnishings, carpets, etc (and perhaps bespoke "treatment" if absolutely necessary) and choose speakers (type especially) that will sound good in the room that has now been significantly improved.
My own large room was dire when I bought this new-build flat, being approx semi-circular with low 7 ft 7 ceilings, floor-to-ceiling glazing on most of the curved wall and hard floors. It had very high reverberation and all-round poor sound. Some speakers were unlistenable to initially. With furnishings, etc and careful choice of speakers, I reckon the sound is pretty good now, and certainly better without applying DSP. I’ve used Dirac, Anthem, MARS and RoomPerfect and always the sound is improved with the filter disengaged.
When you think about it, DSP is a Signal Processor, meaning that the signal is processed such that your amplifier's nice accurate output is deliberately made inaccurate to pander to the poorly treated room, or the poorly chosen or poorly set up speakers. The precious signal should be spared as much processing as possible, so no tone controls, graphic equalisers or any other processor.
To illustrate that DSP damages the signal, try this. Find a piece of music with little bass but plenty of “tingle-factor” top end. Play it via high quality speakers capable of providing this tingle-factor and listen carefully to the top end, with a DSP filter engaged and then with no filter. Although the DSP may not be able to ADJUST these higher frequencies, the fact that the entire frequency range has to pass though the filter (if it’s feeding a full-range amp), the top end suffers and a little of the tingle factor is lost. I’ve tested this many times with other listeners who don’t know if the filter is engaged or not, and most agree that the sound is more life-like and exciting with no filter, even though the bass may be a little flatter if measured with REW. I’d be interested in your own conclusion by doing this simple experiment, if you have suitable speakers chosen carefully for a room that has been thoughtfully furnished.