VAC 200iQ tube monos were a PITA. Just over 100 lbs each, NO handles or grips, and front-heavy with their transformers. Awkward little high-gravity 16" cubes you have to crouch ALL the way down for, to get hands underneath. An then...my horrible death stairs. TWICE. As I get older, I don't want to do deal with that again. The Master 300's are ~ 135 lbs each - and though they do have a "handle" area, I'll be exclusively using hired help (or dealer) for them.
If you are moving stuff, gets some nice grippy Ironclad gloves. They help in all cases, but especially with the grip of cardboard boxes. I learned that far too late!
That said, I'm rather impressed by UPS's handling when I shipped one of 'em off. VAC's packing is perfect - 3" thick of closed-cell foam on every side. That's exactly what you need for the heavy stuff: lots of closed-cell foam. Double or triple wall boxes. I scheduled UPS pickup at home (well worth the $13 service charge!). Amp arrived at destination perfectly, though I made the mistake of separately packing tubes in a much smaller box for the same pickup. THAT box got partially crushed at some point in transit, though (somehow) the tubes were OK. If you do this, make sure to drop off the tubes separately.